1,043 research outputs found

    Cyclic labellings with constraints at two distances

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    Motivated by problems in radio channel assignment, we consider the vertex-labelling of graphs with non-negative integers. The objective is to minimise the span of the labelling, subject to constraints imposed at graph distances one and two. We show that the minimum span is (up to rounding) a piecewise linear function of the constraints, and give a complete specification, together with associated optimal assignments, for trees and cycles

    Human embryos from overweight and obese women display phenotypic and metabolic abnormalities

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    STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight or obese women are smaller than those from women of healthy weight, yet post-fertilization they reach the morula stage faster and, as blastocysts, show reduced glucose consumption and elevated endogenous triglyceride levels. WHAT IS KNOWN ALREADY Female overweight and obesity is associated with infertility. Moreover, being overweight or obese around conception may have significant consequences for the unborn child, since there are widely acknowledged links between events occurring during early development and the incidence of a number of adult disorders. STUDY DESIGN, SIZE, DURATION We have performed a retrospective, observational analysis of oocyte size and the subsequent developmental kinetics of 218 oocytes from 29 consecutive women attending for ICSI treatment and have related time to reach key developmental stages to maternal bodyweight. In addition, we have measured non-invasively the metabolic activity of 150 IVF/ICSI embryos from a further 29 consecutive women who donated their surplus embryos to research, and have related the data retrospectively to their body mass index (BMI). PARTICIPANTS/MATERIALS, SETTING, METHODS In a clinical IVF setting, we compared oocyte morphology and developmental kinetics of supernumerary embryos collected from overweight and obese women, with a BMI in excess of 25 kg/m2 to those from women of healthy weight. A Primovision Time-Lapse system was used to measure developmental kinetics and the non-invasive COnsumption/RElese of glucose, pyruvate, amino acids and lactate were measured on spent droplets of culture medium. Total triglyceride levels within individual embryos were also determined. MAIN RESULTS AND THE ROLE OF CHANCE Human oocytes from women presenting for fertility treatment with a BMI exceeding 25 kg/m2 are smaller (R2 = −0.45; P = 0.001) and therefore less likely to complete development post-fertilization (P < 0.001). Those embryos that do develop reach the morula stage faster than embryos from women of a BMI < 25 kg/m2

    Effects of surface chemistry on hot corrosion life

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    This program has its primary objective: the development of hot corrosion life prediction methodology based on a combination of laboratory test data and evaluation of field service turbine components which show evidence of hot corrosion. The laboratory program comprises burner rig testing by TRW. A summary of results is given for two series of burner rig tests. The life prediction methodology parameters to be appraised in a final campaign of burner rig tests are outlined

    Effects of surface chemistry on hot corrosion life

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    Burner rig tests were conducted under the following conditions: 900 C, hourly thermal cycling, 0.5 ppm sodium as NaCl in the gas stream, and Mach 0.3 velocity. The alloys tested were Udimet 700 (U700) and Rene 80, uncoated and with RT21, Codep, or NiCoCrAlY coatings. The tests, up to 1000 hours, included specimens in the as-processed condition and after aging at 1100 C in oxidizing or inert environments for up to 600 hours. Coil-inductance changes were measured for periodic nondestructive inspection of speciments and found useful in the following course of corrosion. Typical sulfidation observed in all cases was similar to that observed in service-run turbine components. Aging at 1100 C caused severe decrease in the hot corrosion life of RT21 and Codep coatings and a significant but lesser decrease in the life of NiCoCrAlY coatings. The extent of these decreases was much greater for all three coatings on U700 than on Rene substrates. A coating hot corrosion life-predicitin model was proposed. The model requires time/temperature information for a turbine component at takeoff conditions as well as environmental contaminant information

    Network design for urban light transport

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    Using Excel's Solver Function To Facilitate Reciprocal Service Department Cost Allocations

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    The reciprocal method of service department cost allocation requires linear equations to be solved simultaneously.  These computations are often so complex as to cause the abandonment of the reciprocal method in favor of the less sophisticated and theoretically incorrect direct or step-down methods.  This article illustrates how Excel's Solver Function can be used to greatly simplify the reciprocal cost allocation method.  Solver Function users will be pleased to see how easy it is to let Excel do the mathematics once the linear equations are formulated

    Remarks on gauge vortex scattering

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    In the abelian Higgs model, among other situations, it has recently been realized that the head-on scattering of nn solitons distributed symmetrically around the point of scattering is by an angle π/n\pi/n, independant of various details of the scattering. In this note, it is first observed that this result is in fact not entirely surprising: the above is one of only two possible outcomes. Then, a generalization of an argument given by Ruback for the case of two gauge theory vortices in the Bogomol'nyi limit is used to show that in the geodesic approximation the above result follows from purely geometric considerations.Comment: 6 pages, revtex, missing authors added to one referenc

    Comparison of polarisation curves and chronoamperometry experiments of titanium with and without ultrasonic vibrations of the electrolyte

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    Ultrasonic vibrations were applied to the electrolyte in polarisation curve and chronoamperometry to observe the effect of anodic dissolution with the aim to apply to knowledge to electrochemical machining. The application of the ultrasonic vibrations to the electrolyte allowed the dissolution potential to be lowered considerably and the machining rates were increased
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